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Products In Core Medical (Total Products 55, Showing: 1 -> 20)
Abatacept: the evidence for its place in the treatment of rheumatoid arthritis Abatacept: the evidence for its place in the treatment of rheumatoid arthritis
Our Price: £20.00
With its different mechanism of action, abatacept may be an alternative therapy for patients with an inadequate response to other arthritis therapies, especially for those patients with RA refractory to anti-TNF treatment.
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Adalimumab in ankylosing spondylitis: an evidence-based review of its place in therapy Adalimumab in ankylosing spondylitis: an evidence-based review of its place in therapy
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Abbott’s Humira (adalimumab) improves signs and symptoms, inflammation, and quality of life in patients with ankylosing spondylitis, and is cost effective when used according to current guidelines.
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Agomelatine: the evidence for its place in the treatment of depression Agomelatine: the evidence for its place in the treatment of depression
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Agomelatine has good efficacy compared with standard antidepressants for the acute treatment of major depression. In published studies it had a better tolerability profile than SSRIs or SNRIs
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Aliskiren in hypertension: evidence for its potential therapeutic value Aliskiren in hypertension: evidence for its potential therapeutic value
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This Core Evidence proof of concept review on aliskiren, the first in a new class of antihypertensives, reviews the evidence for its use in patients with mild-to-moderate hypertension.
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Anidulafungin: an evidence-based review of its use in invasive fungal infections Anidulafungin: an evidence-based review of its use in invasive fungal infections
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Current evidence supports the use of anidulafungin in the management of candidemia, esophageal candidiasis, and invasive candidiasis as shown by the successful results in large multicenter trials.
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Aprepitant: the evidence for its place in the prevention of chemotherapy-induced nausea and vomiting Aprepitant: the evidence for its place in the prevention of chemotherapy-induced nausea and vomiting
Our Price: £20.00
Despite recent advances, CINV remains a problem for many cancer patients. Merck’s aprepitant, a novel NK1 receptor antagonist, represents a significant advance in highly and moderately emetogenic chemotherapy.
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Aripiprazole: the evidence of its therapeutic impact in schizophrenia Aripiprazole: the evidence of its therapeutic impact in schizophrenia
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Aripiprazole is an atypical antipsychotic suitable for first line use in patients with schizophrenia. This Core Evidence review concludes that it may be particularly useful where tolerability is an issue and in patients with negative symptoms.
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Arzoxifene: the evidence for its development in the management of breast cancer Arzoxifene: the evidence for its development in the management of breast cancer
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Despite early promise as the 'ideal SERM', results from phase III trials have relegated arzoxifene to research in breast cancer prevention and osteoporosis treatment
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Bevacizumab: the evidence for its clinical potential in the treatment of nonsmall cell lung cancer Bevacizumab: the evidence for its clinical potential in the treatment of nonsmall cell lung cancer
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There is clear evidence that bevacizumab extends overall and progression-free survival, and improves response rates in patients with NSCLC, and could have a significant clinical impact according to this Core Evidence review.
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Bortezomib: the evidence of its clinical impact in multiple myeloma Bortezomib: the evidence of its clinical impact in multiple myeloma
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This Core Evidence review presents the evidence supporting bortezomib as a valuable treatment option in patients with multiple myeloma. It is the first and only single agent with evidence of a survival advantage in relapsed or refractory disease.
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Capecitabine: an evidence-based review of its effectiveness in the treatment of carcinoma of the pancreas Capecitabine: an evidence-based review of its effectiveness in the treatment of carcinoma of the pancreas
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This evidence-based review shows that capecitabine can be considered as first-line treatment in combination with gemcitabine to improve response rates and prolong survival by a small but significant margin in patients with advanced pancreatic cancer
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Certolizumab pegol: an evidence-based review of its place in the treatment of Crohn's disease Certolizumab pegol: an evidence-based review of its place in the treatment of Crohn's disease
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Available studies suggest that certolizumab pegol has the potential to achieve and maintain clinical response and remission in moderate to severe Crohn’s disease, and to improve quality of life
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Ciclesonide in persistent asthma: the evidence of its therapeutic value Ciclesonide in persistent asthma: the evidence of its therapeutic value
Our Price: £20.00
The clear evidence for the efficacy and safety of ALTANA’s airway-activated corticosteroid ciclesonide in asthma is evaluated in this Core Evidence review. The lack of effect on adrenal function confers a clinical benefit, particularly in children.
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Dasatinib: the emerging evidence of its potential in the treatment of chronic myeloid leukemia Dasatinib: the emerging evidence of its potential in the treatment of chronic myeloid leukemia
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This Core Evidence emerging therapy review of Dasatinib evaluates the emerging evidence of its potential in the treatment of chronic myeloid leukemia.
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Donepezil in Alzheimer’s disease: an evidence-based review of its impact on clinical and economic outcomes Donepezil in Alzheimer’s disease: an evidence-based review of its impact on clinical and economic outcomes
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This Core Evidence Clinical Impact Review evaluates the clinical impact of donepezil by assessing randomized controlled and open-label naturalistic trials, as well as observational studies.
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Dutasteride: an evidence-based review of its clinical impact in the treatment of benign prostatic hyperplasia Dutasteride: an evidence-based review of its clinical impact in the treatment of benign prostatic hyperplasia
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Dutasteride reduces prostate size in men with BPH according to this Core Evidence clinical impact review, thus providing symptom relief and avoiding the need for surgery.
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Eltrombopag: the emerging evidence of its therapeutic value in thrombocytopenia Eltrombopag: the emerging evidence of its therapeutic value in thrombocytopenia
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GSK’s eltrombopag appears to offer a promising treatment for idiopathic thrombocytopenia purpura, a condition currently without safe options for sustained responses. This Core Evidence article reviews the early evidence.
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Eplerenone: the evidence for its place in the treatment of heart failure after myocardial infarction Eplerenone: the evidence for its place in the treatment of heart failure after myocardial infarction
Our Price: £20.00
This Core Evidence place in therapy review concludes that there is clear evidence of a survival benefit and reduced cardiovascular morbidity and mortality when eplerenone is added to standard treatment in patients with heart failure following
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Eptifibatide: the evidence for its role in the management of acute coronary syndromes Eptifibatide: the evidence for its role in the management of acute coronary syndromes
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This review of the Gp IIb/IIIa inhibitor eptifibatide shows why it has gained widespread acceptance as an adjunct to standard anticoagulation therapy in patients with acute coronary syndromes.
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Eritoran: the evidence of its therapeutic potential in sepsis Eritoran: the evidence of its therapeutic potential in sepsis
Our Price: £20.00
Eritoran is an exciting potential therapeutic option for management of sepsis with a reasonable safety and tolerability profile that must be validated by rigorous randomized clinical trials
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